Ronald Crystal

Ronald Crystal

Company: Weill Cornell Medical College

Job title: Professor & Chair, Department of Genetic Medicine

Seminars:

Evaluating Gene Therapy Distribution & Delivery to the CNS 4:30 pm

Various routes are used for AAV delivery to the CNS, including intravascular, intraventricular, intracisternal magna and intrathecal Using I-124-labeled AAV capsids and positron emission tomography, it is possible to accurately quantify where the vectors immediately distribute Despite the route and the capsid, a significant proportion of CNS administered AAV vector is delivered to organs outside…Read more

day: Day One

Panel Discussion: Discovering Novel Technology for CNS Disorders 5:00 pm

What are the newer procedures for capsid screening platforms for tissue and cell tropism? Which vectors are showing clinical progress? Are there novel vectors showing CNS tropism and selectivity in NHPs? What are the respective challenges for different vector types?Read more

day: Day One

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