Utilising AAV for High Gene Editing in Brain Circuits

Time: 3:30 pm
day: Day One

Details:

  • Improving gene editing safety with different transient Cas9 nuclease expression systems
  • Showing preclinical data for novel AAV-KamiCas9 for in vivo applications in the brain with intrastriatal injection
  • Utilising advanced light sheet microscope to image optically clear specimens according to the CLARITY protocol and multimodal image registration and connectivity analysis (MIRACL) to integrate the Allen brain atlas

Speakers: